Closed-Loop Insulin Delivery Utilizing Pole Placement to Compensate for Delays in Subcutaneous Insulin Delivery
نویسندگان
چکیده
منابع مشابه
Closed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intraperitoneal Insulin Delivery
OBJECTIVE Attempts to build an artificial pancreas by using subcutaneous insulin delivery from a portable pump guided by an subcutaneous glucose sensor have encountered delays and variability of insulin absorption. We tested closed-loop intraperitoneal insulin infusion from an implanted pump driven by an subcutaneous glucose sensor via a proportional-integral-derivative (PID) algorithm. RESEA...
متن کاملClosed-loop insulin delivery for treatment of type 1 diabetes
Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and mortality, and reduced quality of life. Technological innovations positively affect the management of type 1 diabetes. Closed-loop insulin delivery (artificial pancreas) is a recent medical innovation, aiming to reduce the risk of hypogly...
متن کاملFeasibility of Outpatient 24-Hour Closed-Loop Insulin Delivery
Studies using outpatient closed-loop insulin delivery for type 1 diabetes have recently been published (1–5). We conducted a 5-day outpatient feasibility study comparing hybrid closed-loop (HCL) to sensor-augmented pump therapy with low-glucose suspend (SAPT1 LGS) in eight patients with type 1 diabetes using an open-label randomized crossover trial design (ACTRN12614001005640). We used theMedtr...
متن کاملClinical experience with an implanted closed-loop insulin delivery system.
AIM To report the first clinical experience with a prototype of implanted artificial beta-cell. METHODS The Long-Term Sensor System project assessed the feasibility of glucose control by the combined implantation of a pump for peritoneal insulin delivery and a central intravenous glucose sensor, connected physically by a subcutaneous lead and functionally by PID algorithms. It was performed i...
متن کاملModeling Impulsive Insulin Delivery in Insulin Pump with Time Delays
We continue our attempt of modeling the open-loop control of glucose level by impulsive insulin injections. Several time delays exist in the system. The delays include the time needed for insulin from injection depot to transport to the interstitial compartment, the time for the slow inhibition of the hepatic glucose production (HGP), and the time for insulin secretion caused by the elevated gl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Diabetes Science and Technology
سال: 2011
ISSN: 1932-2968,1932-2968
DOI: 10.1177/193229681100500605